Matematisk statistik CTH/GU

Optimal number of measurements needed to prove reduction of exposure

Consider a situation where workers in a working place are exposed to certain airborne chemicals. If a measure is taken to reduce the exposure (such a measure can be ventilation, change of substances etc), it is desirable to have a method to verify that a change has indeed ocurred as a result of the measure taken. One interesting problem in this context is: How many observations do we have to make before and after the preventive measure is taken? Examples of such a situation are reported in the references below. In a large number number of cases, the exposures are measured as the average concentrations in the breathing zone of workers during a shift. Often the variation is so high and the effect of the measure taken is so low, that statistical methods have to be used. The particular distribution used is the lognormal distribution. This problem can be stated as a problem of testing a statistical hypothesis (that the taken measure has no effect vs that it does have an effect) and the power of the test can be used to decide how many observations are needed before and after. References E. Olsen (1994) Analysis of exposure using a logbook method. Appl. Occup. Hyg. 9, 712-722. S.M. Rappaport (1991) Assessment of long-term exposures to toxic substances in air. Ann. Occup. Hyg. 35, 61-121.

Kontaktperson

Ziad Taib, tel: 772 3530, epost: ziad@math.chalmers.se
Last modified: Thu Feb 18 12:04:34 MET 1999